This unit provides a brief review of the history of microdialysis and its general application in the neurosciences. More recently, it has been used in tissue preparations for quantification of neurotransmitter release. It is a widely used method in neuroscience and is one of the few techniques available that permits quantification of neurotransmitters, peptides, and hormones in the behaving animal.
The technique of microdialysis enables sampling and collecting of small-molecular-weight substances from the interstitial space.
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